Microfluidic Devices

Reusable Multi-well Microfluidic Device

• 3D-printed using biocompatible polymer, overcomes limitations of traditional PDMS-based devices.

• Features six wells with removable cell culture inserts and individual media collection ports for easy operation.

• Optimized for improved handling and easy post-processing of tissues during experiments.

• Validation: Validated for co-culture of cells of upper respiratory tract

Perfusion Microfluidic Mammalian Co-culture Device

• Features a central culture chamber with a removable insert, enabling air-interface exposure of the cells.

• Removable frame allows easy imaging and reinsertion for continued culture.

• Fabrication: Compatible with 3D printing, injection molding, or CNC milling.

• Validation: Validation for co-culture of skin fibroblasts and keratinocytes.

Microfluidic Cellular Communication Device

• Designed with two interconnected chambers allowing media flow through microchannels.

• Facilitates communication between chambers for experimental interaction studies.

• Fabricated using PDMS for biocompatibility and ease of molding.

• Validation: Supports co-culture of retinal epithelial cells and photoreceptor cells.

Microfluidic Platform for Developing In-vitro Co-cultures of Mammalian Tissues

• Includes single cell culture chamber layer with porous membrane.

• Supports media and scaffold-guided 3D tissue or organ-like cellular orientation.

• Compatible with biopolymer scaffolds such as collagen, chitosan, and cellulose.

• Fabricated using PDMS for biocompatibility and ease of molding.

• Validation: Validation for co-culture of skin fibroblasts and keratinocytes.